● Aerosol generator for compressed dry powders

● Computer-controlled via special software

● Adjustable feedrate (0.24 – 20 mm/h) and rotation speed (0 – 800 rev/h)

● Specially designed substance scraper with exchangeable blades

● Stable generation of a uniform test atmosphere

● Stable particle size distribution over a long period

Chemico-Biological Interactions 2013; 206:479-490

"Use of the Cultex® Radial Flow System as an in vitro exposure method to assess acute pulmonary toxicity of fine dusts and nanoparticles with special focus on the intra- and inter-laboratory reproducibility"

Authors: D. Steinritz, N. Möhle, C. Pohl, M. Papritz, B. Stenger, A. Schmidt, C. J. Kirkpatrick, H. Thiermann, R. Vogel, S. Hoffmann, M. Aufderheide

IVTIP 2013, Southhampton

"Prevalidation of the CULTEX® method (BMBF project 0315710): The air-liquid interface exposure of human lung cells in the CULTEX® Radial Flow System (RFS)"

Authors: N. Möhle, D. Steinritz, C. Pohl, S. Hoffmann, M. Aufderheide

Eurotox 2011, Paris

"Prevalidation of the CULTEX® method: in vitro analysis of the acute toxicity of inhalable fine dusts and nanoparticles after direct exposure of cultivated human cells from the respiratory tract"

Authors: C. Pohl, N. Möhle, M. Papritz, D. Steinritz, U. Mohr, S. Hoffmann, C.J. Kirkpatrick, M. Aufderheide

In vitro World Congress 2011, Montreal

"Pre-validation of the CULTEX® system assessing the acute inhalation toxicity of nanoparticles by direct exposure of cells via the air-liquid interface"

Authors: S. Hoffmann, N. Möhle, M. Papritz, C. Pohl, M. Aufderheide